Thomas K. Chambers, in 1848, announced that he believed the inhalation of powder would allow for the direct application of medicine to the lungs, which are otherwise "inaccessible." For doing this he introduced a glass funnel of his own design specifically made to inhale a very fine powder of pollen of lycopodium or club moss with nitrate of silver or sulphate of copper, or both. (1) (2)
The device and how to use it was described by Chambers in the Boston Medical and Surgical Journal:
The patient should introduce into his mouth, as far as he can without choking, a well-dried glass funnel, and draw in his breath strongly, whilst he himself, or a second parly, dusts the powder in a dense cloud into the large end with an ordinary nursery puff-ball. If the dust is raised by an attendant, the patient can indicate the moment he inspires by raising his hand.
To obviate the necessity for withdrawing the funnel after each inhalation, to prevent the dust being blown about the room, an apparatus with a double valve and a closed powder-box may be used, which allows the dust to pass inwards only; but the necessary employment of metal makes the machine less agreeable than the more awkward but cleanerlooking and less formidable glass.
- Sanders, Mark, "Pioneers of Inhalation," Inhalatorium.com, a slideshow by Mark Sanders, http://www.ddl-conference.org.uk/files/DDL20presentations/19.Sanders.pdf
- Chambers, Thomas, "Inhalation of Nitrate of Silver,"Boston Medical and Surgical Journal, February to August, 1849, Edited by J.V.C. Smith, Volume XL, Boston, David Clapp, pages 394-5